{"id":2102,"date":"2021-12-29T19:30:59","date_gmt":"2021-12-29T18:30:59","guid":{"rendered":"https:\/\/www.devatec.com\/?p=2102"},"modified":"2023-03-22T16:07:38","modified_gmt":"2023-03-22T15:07:38","slug":"humidification-against-sick-building-syndrome","status":"publish","type":"post","link":"https:\/\/www.devatec.com\/en\/humidification-against-sick-building-syndrome\/","title":{"rendered":"Humidification against Sick Building Syndrome"},"content":{"rendered":"\n<pre class=\"wp-block-verse\">Relative humidity between 40% and 60% helps to :\n\u2022 Reduce infection transmission,\n\u2022 Reduce bioaerosol infectivity,\n\u2022 Reduce SBS disorders.<\/pre>\n\n\n\n<h4 class=\"wp-block-heading\">SICK BUILDING SYNDROME (SBS)<\/h4>\n\n\n\n<p>It defines the symptoms of health disorders suffered by building occupants. The longer a person stays<br>in the building, the worse their symptoms get. An improvement generally occurs when people leave<br>the building.<br>Symptoms may include dry eyes, headaches, tiredness, dry skin, rashes, blocked or runny nose and<br>result in a high absenteeism rate.<\/p>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"184\" height=\"160\" data-id=\"851\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p1_2-2.png\" alt=\"\" class=\"wp-image-851\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"361\" height=\"314\" data-id=\"853\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p1_3-1.png\" alt=\"\" class=\"wp-image-853\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p1_3-1.png 361w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p1_3-1-300x261.png 300w\" sizes=\"auto, (max-width: 361px) 100vw, 361px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"344\" height=\"304\" data-id=\"855\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p1_8.png\" alt=\"\" class=\"wp-image-855\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p1_8.png 344w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p1_8-300x265.png 300w\" sizes=\"auto, (max-width: 344px) 100vw, 344px\" \/><\/figure>\n<\/figure>\n\n\n\n<p>Several interrelated physical factors such as inadequate ventilation, uncomfortable temperatures, low<br>relative humidity and poor lighting can have a cumulative effect and increase the severity of SBS(1).<\/p>\n\n\n\n<p><strong>When the indoor relative humidity is about 40% to 60% (7 to 10 grams of moisture per kg of dry air), symptoms like dry skin, dry eyes, stuffy nose and respiratory infection are reduced.<\/strong><\/p>\n\n\n\n<p><strong>Maintaining the right indoor climate and controlled humidification also allows to reduce the heating<br>costs: 1\u00b0C of heating can be saved by increasing the relative humidity from 20% to 50%.<\/strong><\/p>\n\n\n\n<p>(A 10% increase in relative humidity results in a feeling of warmth equivalent to a 0.3\u00b0C increase in operating temperature(2))<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"407\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.20.14-1024x407.png\" alt=\"\" class=\"wp-image-2104\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.20.14-1024x407.png 1024w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.20.14-300x119.png 300w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.20.14-768x305.png 768w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.20.14-1536x610.png 1536w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.20.14.png 1752w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Adequate relative humidity protects your eyes<\/h2>\n\n\n\n<pre class=\"wp-block-verse\">A relative humidity maintained between 40%-60% helps prevent the evaporation\nof the lacrimal film and SBS disorders associated with.<\/pre>\n\n\n\n<div class=\"wp-block-media-text alignwide is-stacked-on-mobile\" style=\"grid-template-columns:41% auto\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"900\" height=\"574\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p2_9.png\" alt=\"\" class=\"wp-image-859 size-full\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p2_9.png 900w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p2_9-300x191.png 300w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p2_9-768x490.png 768w\" sizes=\"auto, (max-width: 900px) 100vw, 900px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<p>Tear or tear film is a thin, almost invisible barrier that<br>covers the eye. It consists of three very thin layers (lipid, water and mucin layers). Its function is to protect<br>the ocular surface (eye, cornea and conjunctiva) against<br>irritation and infections. <strong>The low relative humidity is a<br>proven risk factor for developing Dry Eye disease<\/strong>(3).<\/p>\n\n\n\n<p>Fine dust particles (allergens and pathogens) can<br>penetrate the conjunctiva through cracks in the tear film<br>layers. The thickness of the tear film also depends on<br>air humidity.<\/p>\n<\/div><\/div>\n\n\n\n<p>If room air is kept dry, evaporation of tear fluid increases. Eye and conjunctiva irritation affects visual<br>performance, which can lead to fatigue, dizziness and headaches due to tension in the forehead, back<br>of the head or neck.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"662\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.22.38-1024x662.png\" alt=\"\" class=\"wp-image-2106\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.22.38-1024x662.png 1024w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.22.38-300x194.png 300w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.22.38-768x497.png 768w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.22.38-1536x993.png 1536w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.22.38.png 1998w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Thanks to controlled air humidification, dry eye strain complaints are 50% reduced(6).<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Adequate relative humidity protects your skin<\/h2>\n\n\n\n<pre class=\"wp-block-verse\">Maintaining a relative humidity between 40 % and 60 % prevents from dehydration\nof NMF (natural moisturizing factors) and SBS disorders associated with dry skin.<\/pre>\n\n\n\n<p>Patients with atopic dermatitis or psoriasis generally experience worsening symptoms in winter(7) and<br>dry environments produced by air conditioning or central heating. In general, increased skin roughness can be observed after 3 hours of exposure to 30% relative humidity(8).<\/p>\n\n\n\n<div class=\"wp-block-media-text alignwide has-media-on-the-right is-stacked-on-mobile\"><div class=\"wp-block-media-text__content\">\n<p>Skin is the largest organ of the human body and acts<br>as a self-healing barrier that protects against shocks,<br>dangerous chemicals or microorganisms. It also prevents from the uncontrolled loss of water and is important for thermoregulation of our body (homeostasis)(9).<br>Skin is composed of several layers (epidermis, dermis<br>and hypodermis) and sub-layers, including the stratum<br>corneum (SC), which is the outer part of the epidermis.<br><strong>In a dry air environment, the skin will be dehydrated<br>and loose its protective abilities.<\/strong><\/p>\n<\/div><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"528\" height=\"220\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p3_12.png\" alt=\"\" class=\"wp-image-863 size-full\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p3_12.png 528w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p3_12-300x125.png 300w\" sizes=\"auto, (max-width: 528px) 100vw, 528px\" \/><\/figure><\/div>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"451\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.24.57-1024x451.png\" alt=\"\" class=\"wp-image-2108\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.24.57-1024x451.png 1024w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.24.57-300x132.png 300w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.24.57-768x338.png 768w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.24.57-1536x676.png 1536w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.24.57.png 1722w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>Skin has a very low permeability, it is not totally tight(10). At a constant air temperature, moisturization of<br>the skin increases with the humidity of the air(11,12) thanks to the sorption ability of the SC, NMF and SC<br>lipids<\/p>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-2 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1012\" height=\"862\" data-id=\"2110\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.27.03.png\" alt=\"\" class=\"wp-image-2110\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.27.03.png 1012w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.27.03-300x256.png 300w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.27.03-768x654.png 768w\" sizes=\"auto, (max-width: 1012px) 100vw, 1012px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1016\" height=\"834\" data-id=\"2112\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.27.07.png\" alt=\"\" class=\"wp-image-2112\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.27.07.png 1016w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.27.07-300x246.png 300w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.27.07-768x630.png 768w\" sizes=\"auto, (max-width: 1016px) 100vw, 1016px\" \/><\/figure>\n<\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Adequate relative humidity protects your nose mucosa<\/h2>\n\n\n\n<pre class=\"wp-block-verse\">Maintaining relative humidity between 40%-60% helps prevent from cold nose and nosebleeds.<\/pre>\n\n\n\n<p>Nose is the access to our lungs, and its mucous membrane filter heats and humidifies the air we breath.<br>It is equipped with sensors that analyze smell and degree of heat (hot\/cold) in the air(13). The nasal<br>mucous membrane can be damaged by prolonged exposure to dry air, making it more vulnerable to<br>congestion and infection.<\/p>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-3 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"888\" height=\"670\" data-id=\"2114\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.28.06.png\" alt=\"\" class=\"wp-image-2114\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.28.06.png 888w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.28.06-300x226.png 300w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.28.06-768x579.png 768w\" sizes=\"auto, (max-width: 888px) 100vw, 888px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"586\" data-id=\"2116\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.28.14-1024x586.png\" alt=\"\" class=\"wp-image-2116\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.28.14-1024x586.png 1024w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.28.14-300x172.png 300w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.28.14-768x440.png 768w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/12\/Capture-de\u0301cran-2021-12-29-a\u0300-19.28.14.png 1090w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/figure>\n\n\n\n<div class=\"wp-block-media-text alignwide is-stacked-on-mobile\" style=\"grid-template-columns:33% auto\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"545\" height=\"515\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p4_20.png\" alt=\"\" class=\"wp-image-876 size-full\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p4_20.png 545w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p4_20-300x283.png 300w\" sizes=\"auto, (max-width: 545px) 100vw, 545px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<p>When nasal hair cells are damaged, they are replaced by goblet cells, resulting in hypersecretion of mucin. The loss of hair cells also decreases<br>mucociliary activity (14), resulting in changes in mucociliary clearance:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>nasal congestion.<\/li>\n\n\n\n<li>the respiratory tract is altered, making it more susceptible to infections<br>(15), such as those caused by rhinovirus (cold) and influenza virus (flu).<br>Human rhinoviruses account for more than 50 % of upper respiratory<br>tract infections. They may also lead to sinusitis, bronchitis, bronchiolitis,<br>hypothermia, sore throat, and otitis media.<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p><strong>Low humidity increases the incidence of influenza outbreaks.<\/strong> High transmission and infectivity of<br>respiratory viruses is strongly associated with low relative humidity. To reduce risks, it is important to<br>maintain indoor relative humidity between 40% and 60% (16,17).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Adequate relative humidity prevents ESD<\/h2>\n\n\n\n<div class=\"wp-block-media-text alignwide has-media-on-the-right is-stacked-on-mobile\" style=\"grid-template-columns:auto 18%\"><div class=\"wp-block-media-text__content\">\n<p>ESD is a particularly dangerous phenomenon because you are the source of<br>these transients. It is the static electricity which builds up on your body. The<br>jolt you get from touching a doorknob or shaking someone\u2019s hand is ESD18.<br>Maintaining relative humidity between 40% and 60%, reduces the accumulation of static electricity in the air, and eliminates its consequences :<br>discharges in contact with other people or metal objects, clothing charged<br>with static electricity\u2026<\/p>\n<\/div><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"279\" height=\"351\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p5_22.png\" alt=\"\" class=\"wp-image-880 size-full\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p5_22.png 279w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p5_22-238x300.png 238w\" sizes=\"auto, (max-width: 279px) 100vw, 279px\" \/><\/figure><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"630\" height=\"345\" src=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p5_21.png\" alt=\"\" class=\"wp-image-878\" srcset=\"https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p5_21.png 630w, https:\/\/www.devatec.com\/wp-content\/uploads\/2021\/10\/p5_21-300x164.png 300w\" sizes=\"auto, (max-width: 630px) 100vw, 630px\" \/><\/figure>\n<\/div>\n\n\n<pre class=\"wp-block-verse\"><strong>Sources<\/strong>:\n1) Sick building syndrome, World Health Organization Regional Office for Europe : https:\/\/www.wondermakers.com\/Portals\/0\/docs\/Sick%20building%20syndrome%20by%20\n WHO.pdf\n 2) ISO 7730:2005 Ergonomics of the thermal environment \u2014 Analytical determination and interpretation of thermal comfort using calculation of the PMV and PPD indices and\n local thermal comfort criteria\n 3) Song P, Xia W, Wang M, et al. Variations of dry eye disease prevalence by age, sex and geographic characteristics in China: a systematic review and meta-analysis. J Glob\n Health. 2018;8(2):020503. doi:10.7189\/jogh.08.020503a systematic review and meta-analysis\n 4)Rolando M, Valente C. Establishing the tolerability and performance of tamarind seed polysaccharide (TSP) in treating dry eye syndrome: results of a clinical study. BMC Ophthalmol. 2007;7:5. Published 2007 Mar 29. doi:10.1186\/1471-2415-7-5\n 5) Mantelli F, Arg\u00fceso P. Functions of ocular surface mucins in health and disease. Curr Opin Allergy Clin Immunol. 2008;8(5):477-483. doi:10.1097\/ACI.0b013e32830e6b04\n 6) Stefan Rief\u2006| Mitja Jurec i c LUFTFEUCHTIGKEIT AM B\u00dcROARBEITSPLATZ\n 7) Denda M, Sato J, Tsuchiya T, Elias PM, Feingold KR. Low humidity stimulates epidermal DNA synthesis and amplifies the hyperproliferative response to barrier disruption:\n implication for seasonal exacerbations of inflammatory dermatoses. The Journal of Investigative Dermatology. 1998 Nov;111(5):873-878. DOI: 10.1046\/j.1523-1747.1998.00364.x.\n 8)Spiegl, A.: Einfluss der Luftfeuchtigkeit auf die Hautrauhigkeit bei Patienten mit atopischem Ekzem. Dissertation Universit\u00e4t M\u00fcnchen 1998.\n 9) Augustijns, Patrick &amp; Brewster, Marcus. (2007). Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics. 10.1007\/978-0-387-69154-1.\n 10) Silva, C.L. &amp; Topgaard, D &amp; Kocherbitov, Vitaly &amp; Sousa, Joao &amp; Pais, Alberto &amp; Sparr, Emma. (2007). Stratum corneum hydration: Phase transformations and mobility in stratum\n corneum, extracted lipids and isolated corneocytes. Biochimica et biophysica acta. 1768. 2647-59. 10.1016\/j.bbamem.2007.05.028.\n 11) Mole R. H. (1948). The relative humidity of the skin. The Journal of physiology, 107(4), 399\u2013411. https:\/\/doi.org\/10.1113\/jphysiol.1948.sp004284\n 12) Wildnauer RH, Bothwell JW, Douglass AB. Stratum corneum biomechanical properties. I. Influence of relative humidity on normal and extracted human stratum corneum. J\n Invest Dermatol. 1971;56(1):7278. doi:10.1111\/1523-1747.ep12292018\n 13) Baraniuk JN, Merck SJ. Neuroregulation of human nasal mucosa. Ann N Y Acad Sci. 2009;1170:604-609. doi:10.1111\/j.1749-6632.2009.04481.x\n 14) Bernstein, Jonathan &amp; Singh, Umesh. (2015). Neural Abnormalities in Nonallergic Rhinitis. Current allergy and asthma reports. 15. 511. 10.1007\/s11882-015-0511-7.\n 15) Blaas D, Fuchs R. Mechanism of human rhinovirus infections. Mol Cell Pediatr. 2016;3(1):21. doi:10.1186\/s40348-016-0049-3\n 16) Lowen AC, Mubareka S, Steel J, Palese P. Influenza virus transmission is dependent on relative humidity and temperature. PLoS Pathog. 2007;3(10):1470-1476. doi:10.1371\/\n journal.ppat.0030151\n 17) Kudo E, Song E, Yockey LJ, Rakib T, Wong PW, et al. 2019. Low ambient humidity impairs barrier function and innate resistance against influenza infection. PNAS 116:10905\u201310\n 18) Armstrong Handbook HB-501 - 11\/97\n 08\/2020\n <strong>Author<\/strong>: P.E. David, Pharmacist and HVAC specialist at Armstrong International<\/pre>\n","protected":false},"excerpt":{"rendered":"<p>Relative humidity between 40% and 60% helps to : \u2022 Reduce infection transmission, \u2022 Reduce bioaerosol infectivity, \u2022 Reduce SBS disorders. SICK BUILDING SYNDROME (SBS) It defines the symptoms of health disorders suffered by building occupants. The longer a person staysin the building, the worse their symptoms get. An improvement generally occurs when people leavethe building.Symptoms may include dry eyes, headaches, tiredness, dry skin, rashes, blocked or runny nose andresult in a high absenteeism rate. Several interrelated physical factors such as inadequate ventilation, uncomfortable temperatures, lowrelative humidity and poor lighting can have a cumulative effect and increase the severity of SBS(1). When the indoor relative humidity is about 40% to 60% (7 to 10 grams of moisture per kg of dry air), symptoms like dry skin, dry eyes, stuffy nose and respiratory infection are reduced. Maintaining the right indoor climate and controlled humidification also allows to reduce the heatingcosts: 1\u00b0C of heating can be saved by increasing the relative humidity from 20% to 50%. (A 10% increase in relative humidity results in a feeling of warmth equivalent to a 0.3\u00b0C increase in operating temperature(2)) Adequate relative humidity protects your eyes A relative humidity maintained between 40%-60% helps prevent the evaporation of the lacrimal film and SBS disorders associated with. Tear or tear film is a thin, almost invisible barrier thatcovers the eye. It consists of three very thin layers (lipid, water and mucin layers). Its function is to protectthe ocular surface (eye, cornea and conjunctiva) againstirritation and infections. The low relative humidity is aproven risk factor for developing Dry Eye disease(3). Fine dust particles (allergens and pathogens) canpenetrate the conjunctiva through cracks in the tear filmlayers. The thickness of the tear film also depends onair humidity. If room air is kept dry, evaporation of tear fluid increases. Eye and conjunctiva irritation affects visualperformance, which can lead to fatigue, dizziness and headaches due to tension in the forehead, backof the head or neck. Adequate relative humidity protects your skin Maintaining a relative humidity between 40 % and 60 % prevents from dehydration of NMF (natural moisturizing factors) and SBS disorders associated with dry skin. Patients with atopic dermatitis or psoriasis generally experience worsening symptoms in winter(7) anddry environments produced by air conditioning or central heating. In general, increased skin roughness can be observed after 3 hours of exposure to 30% relative humidity(8). Skin is the largest organ of the human body and actsas a self-healing barrier that protects against shocks,dangerous chemicals or microorganisms. It also prevents from the uncontrolled loss of water and is important for thermoregulation of our body (homeostasis)(9).Skin is composed of several layers (epidermis, dermisand hypodermis) and sub-layers, including the stratumcorneum (SC), which is the outer part of the epidermis.In a dry air environment, the skin will be dehydratedand loose its protective abilities. Skin has a very low permeability, it is not totally tight(10). At a constant air temperature, moisturization ofthe skin increases with the humidity of the air(11,12) thanks to the sorption ability of the SC, NMF and SClipids Adequate relative humidity protects your nose mucosa Maintaining relative humidity between 40%-60% helps prevent from cold nose and nosebleeds. Nose is the access to our lungs, and its mucous membrane filter heats and humidifies the air we breath.It is equipped with sensors that analyze smell and degree of heat (hot\/cold) in the air(13). The nasalmucous membrane can be damaged by prolonged exposure to dry air, making it more vulnerable tocongestion and infection. Low humidity increases the incidence of influenza outbreaks. High transmission and infectivity ofrespiratory viruses is strongly associated with low relative humidity. To reduce risks, it is important tomaintain indoor relative humidity between 40% and 60% (16,17). Adequate relative humidity prevents ESD ESD is a particularly dangerous phenomenon because you are the source ofthese transients. It is the static electricity which builds up on your body. Thejolt you get from touching a doorknob or shaking someone\u2019s hand is ESD18.Maintaining relative humidity between 40% and 60%, reduces the accumulation of static electricity in the air, and eliminates its consequences :discharges in contact with other people or metal objects, clothing chargedwith static electricity\u2026 Sources: 1) Sick building syndrome, World Health Organization Regional Office for Europe : https:\/\/www.wondermakers.com\/Portals\/0\/docs\/Sick%20building%20syndrome%20by%20 WHO.pdf 2) ISO 7730:2005 Ergonomics of the thermal environment \u2014 Analytical determination and interpretation of thermal comfort using calculation of the PMV and PPD indices and local thermal comfort criteria 3) Song P, Xia W, Wang M, et al. Variations of dry eye disease prevalence by age, sex and geographic characteristics in China: a systematic review and meta-analysis. J Glob Health. 2018;8(2):020503. doi:10.7189\/jogh.08.020503a systematic review and meta-analysis 4)Rolando M, Valente C. Establishing the tolerability and performance of tamarind seed polysaccharide (TSP) in treating dry eye syndrome: results of a clinical study. BMC Ophthalmol. 2007;7:5. Published 2007 Mar 29. doi:10.1186\/1471-2415-7-5 5) Mantelli F, Arg\u00fceso P. Functions of ocular surface mucins in health and disease. Curr Opin Allergy Clin Immunol. 2008;8(5):477-483. doi:10.1097\/ACI.0b013e32830e6b04 6) Stefan Rief\u2006| Mitja Jurec i c LUFTFEUCHTIGKEIT AM B\u00dcROARBEITSPLATZ 7) Denda M, Sato J, Tsuchiya T, Elias PM, Feingold KR. Low humidity stimulates epidermal DNA synthesis and amplifies the hyperproliferative response to barrier disruption: implication for seasonal exacerbations of inflammatory dermatoses. The Journal of Investigative Dermatology. 1998 Nov;111(5):873-878. DOI: 10.1046\/j.1523-1747.1998.00364.x. 8)Spiegl, A.: Einfluss der Luftfeuchtigkeit auf die Hautrauhigkeit bei Patienten mit atopischem Ekzem. Dissertation Universit\u00e4t M\u00fcnchen 1998. 9) Augustijns, Patrick &amp; Brewster, Marcus. (2007). Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics. 10.1007\/978-0-387-69154-1. 10) Silva, C.L. &amp; Topgaard, D &amp; Kocherbitov, Vitaly &amp; Sousa, Joao &amp; Pais, Alberto &amp; Sparr, Emma. (2007). Stratum corneum hydration: Phase transformations and mobility in stratum corneum, extracted lipids and isolated corneocytes. Biochimica et biophysica acta. 1768. 2647-59. 10.1016\/j.bbamem.2007.05.028. 11) Mole R. H. (1948). The relative humidity of the skin. The Journal of physiology, 107(4), 399\u2013411. https:\/\/doi.org\/10.1113\/jphysiol.1948.sp004284 12) Wildnauer RH, Bothwell JW, Douglass AB. Stratum corneum biomechanical properties. I. Influence of relative humidity on normal and extracted human stratum corneum. J Invest Dermatol. 1971;56(1):7278. doi:10.1111\/1523-1747.ep12292018 13) Baraniuk JN, Merck SJ. 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